The Biochemistry and Immunology of Cancer Program focuses on fundamental mechanisms of cancer initiation, progression, and prevention. Emphasis is placed on molecular studies encompassing structure, function, interaction, signaling, and regulatory pathways. The following areas of research are relevant to this program:
- Genetic and epigenetic regulation of gene expression
- Mechanisms of DNA damage/repair and genomic instability
- Functional and structural analysis of macromolecules including DNA, RNA and proteins
- Protein modification, structure, function, interactions with nucleic acids or proteins and degradation
- Cellular metabolism and signaling
- Basic mechanisms of tumor immunology and hematologic malignancies