Key Statistics for Endometrial Cancer

In the United States, cancer of the endometrium (the lining of the uterus) is the most common cancer of the female reproductive organs.

How common is endometrial cancer?

The American Cancer Society estimates for cancer of the uterus in the United States for 2025 are:

• About 69,120 new cases of cancer of the uterus will be diagnosed.
• About 13,860 women will die from cancers of the uterus.

These estimates include both endometrial cancers and uterine sarcomas. Up to 10% of uterine cancers are sarcomas, so the actual numbers for endometrial cancer cases and deaths are slightly lower than these estimates.

Who gets endometrial cancer?

Endometrial cancer is the fourth most common cancer for women in the United States. Worldwide, an estimated 417,367 cases of endometrial cancer were diagnosed in 2020.

About 69% of uterine cancers are diagnosed when the cancer is in an early stage. This is largely because abnormal vaginal bleeding is an early symptom. particularly when it occurs after menopause. Anyone with vaginal bleeding after menopause should tell their doctor.

Endometrial cancer affects mainly post-menopausal women. The average age of women diagnosed with endometrial cancer is 60. It's uncommon in women under the age of 45.

This cancer is more common in Black women than in White women.

Incidence trends

Incidence has increased by more than 1% per year since the mid-2000s; over the past decade (2012-2021), the rate increased by 0.6% per year in White women and 2% to 3% per year in women of all other racial and ethnic groups.

Mortality trends

Uterine cancer is one of the few cancers with increasing mortality; from  from 2013 to 2022 the death rate rose by 1.5% per year. .

There are more than 600,000 survivors of endometrial cancer in the US today.

In 2020, an estimated 97,370 people worldwide died from uterine cancer.

Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.