Fertility Assistance and Other Options for Becoming a Parent After Cancer

Assisted Reproduction

If you or your partner cryopreserved (froze) your embryos, eggs, or sperm, you’ll want to work with a fertility specialist to decide on your next steps.

Depending on your situation, you might be able to have a child in one of these ways:

Embryo transfer

For embryo transfer, cryopreserved embryos are thawed and tested to make sure they are in good shape. They are then placed into a woman’s uterus during the right part of her menstrual cycle. Some women may need hormone therapy to get their cycle into the right place before the embryo is transferred.

Intrauterine insemination (IUI)

Intrauterine insemination might be a possibility if a man’s sperm are cryopreserved and his female partner is fertile. After the sperm is thawed, it’s put into the woman’s uterus using a long, flexible tube called a catheter. If you choose this option, you’ll work with a fertility specialist to figure out the best time to do this.

In vitro fertilization (IVF)

In vitro fertilization can be done using either frozen eggs or frozen sperm. The eggs are put in a sterile lab dish with several thousand sperm. The goal is for one of the sperm to fertilize the egg. If an egg is fertilized, the embryo can be put into the woman’s uterus to try and start a pregnancy.

In vitro fertilization with intracytoplasmic sperm injection (IVF-ICSI)

With IVF-ICSI, a single sperm is injected directly into an egg to fertilize it in a lab. If the egg is fertilized, the embryo can be put into a woman’s uterus to try and start a pregnancy.

Options for women who are not fertile after cancer treatment

You might not be able to freeze your eggs or embryos before cancer treatment. Or you may not be able to carry a pregnancy. If so, there are other options you can explore.

Donor eggs

If you weren’t able to freeze your eggs or embryos, donor eggs might be an option. You’ll use in vitro fertilization (IVF) for this.

The donor eggs are fertilized with your partner’s sperm, or with donor sperm. These embryos are then transferred to your uterus to try and start a pregnancy.

The success of the egg donation depends on careful timing. You’ll use hormone treatments to make sure the lining of your uterus is ready for an embryo to be placed inside. You might need continued hormone support until the placenta develops and can make its own hormones.

Where do donor eggs come from?

Donated eggs come from women who have volunteered to have their eggs collected. Egg donors can be known or anonymous. Some people have a sister, cousin, or close friend who is willing to donate her eggs without payment. There are also frozen egg banks available. You can purchase frozen eggs from one of these banks. The eggs are then sent to a fertility center for IVF.

How are donors screened?

Egg donors are carefully screened for sexually transmitted infections and genetic diseases. In many cases, donors are also screened by a mental health professional; this screening is strongly recommended. Mental health screenings are just as important if your donor is a friend or family member.

If your egg donor is known (not anonymous), everyone also needs to agree on the donor’s future relationship with the child. Everyone needs to be certain that the donor was not pressured to donate her eggs.

Donor embryos

If your uterus is healthy and your body can maintain a pregnancy, you might be able to get pregnant using donor embryos. Most people who use donor embryos have to get hormone treatments to prepare the lining of the uterus and ensure the best timing of the embryo transfer. So you also must be able to safely take hormones.

These embryos use donor sperm and donor eggs. They do not use sperm or an egg from you or your partner. This option lets you experience pregnancy and birth, but you won’t have a genetic relationship to the child. Embryo donations usually come from a couple who had IVF and has extra frozen embryos.

How are embryo donors screened?

Embryo donors must go through screening and testing before they can donate. They are tested for infectious diseases and are asked about their medical and genetic history. However, donors don’t always give a detailed health history, so the risk of the embryo carrying an infection or genetic changes can’t be eliminated.

How much do donor embryos cost?

Donor embryos are usually free, but there are other costs to the procedure. You will likely need to take medicines to get your uterus ready for the embryo. Having the embryo placed in your uterus is a medical procedure, so it carries a cost. There might also be legal fees.

Gestational carriers and surrogates

Some women can’t carry a pregnancy after cancer treatment, either because they no longer have a working uterus, or because they would be at high risk for a health problem if they got pregnant. In that case, having another woman carry the baby might be an option. This is done either through a gestational carrier or through a surrogate.

Gestational carriers

A gestational carrier is the most common option. This is a healthy woman who carries the embryos created from the egg and sperm of the intended parents, or from egg or sperm donors. The gestational carrier doesn’t contribute her own egg to the embryo. She has no genetic relationship to the baby.

Surrogates

A traditional surrogate is used much less often. It is illegal in some states.

A surrogate becomes pregnant through artificial insemination. This is done either with sperm from a man who will raise the child, or from a sperm donor. The surrogate gives her own egg. It is fertilized with the sperm in a lab. The surrogate carries the pregnancy. She is the genetic mother of the baby.

Surrogacy can be a legally complicated and expensive process. Surrogacy laws vary, so it’s important to have a lawyer help you make the legal arrangements with your surrogate.

You should review the laws of the state where the surrogate lives, the state where the child will be born, and the state where you live. It’s also very important that the surrogate be evaluated and supported by an expert mental health professional as part of the process. This can help prevent problems when the child is born.

Donor sperm for men who are not fertile after cancer treatment

If you couldn’t freeze your sperm before cancer treatment, using donor sperm might be an option.  

Major sperm banks in the United States collect sperm from young men who volunteer. They go through a detailed screening of their physical health, family health history, educational and emotional history, and even some genetic testing.

Donors are also tested for sexually transmitted diseases, including HIV and hepatitis viruses. You might be able to choose between a donor who will remain anonymous, one who provides personal information but doesn’t want his identity known, or one who is willing to have contact with the child later in life.

The donor sperm is then used in an assisted reproduction process. This is usually done through intrauterine insemination (IUI).

The cost of donor sperm and the IUI procedure varies. If you're interested in this approach, check with your insurance company about coverage and ask your fertility specialist what costs are involved with the process. Be sure to ask for a list of all fees and charges, since these differ from one center to another.

Adoption

Adoption might be an option if you’ve had cancer and want to become a parent. You will likely be asked to answer questions about your health. You may also need to submit a letter from your doctor describing your cancer status and prognosis.

There are adoption agencies that have experience working with cancer survivors. Cancer survivors also have some legal protections under the Americans with Disabilities Act (ADA). This includes protection against discrimination during adoption proceedings.

You can adopt a child in your own country through a public agency (such as the foster care system), through a private agency, or by a private arrangement. Private agencies may also help with international adoptions. The adoption process takes different lengths of time depending on the type of adoption you choose.

Adoption is complex and requires a lot of paperwork. Many people find it helpful to attend adoption or parenting classes before adopting. These classes can help you understand the adoption process and give you a chance to meet other people in similar situations.

The cost of adoption varies greatly. It ranges from around $6,000 (for a public agency, foster care, or special needs adoption) to between $20,000 and $50,000 (for private U.S. and some international adoptions, including travel costs).

Choosing not to have children

Many people, with or without cancer, decide they prefer not to have children. If you are unsure about having children, talk with your spouse or partner. If you are having trouble agreeing on the future, talking with a counselor or mental health professional may help you both think more clearly about the issues and make the best decision.

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