Español
PDFs by language
Our 24/7 cancer helpline provides information and answers for people dealing with cancer. We can connect you with trained cancer information specialists who will answer questions about a cancer diagnosis and provide guidance and a compassionate ear.
Chat live online
Select the Live Chat button at the bottom of the page
Call us at 1-800-227-2345
Available any time of day or night
Our highly trained specialists are available 24/7 via phone and on weekdays can assist through video calls and online chat. We connect patients, caregivers, and family members with essential services and resources at every step of their cancer journey. Ask us how you can get involved and support the fight against cancer. Some of the topics we can assist with include:
For medical questions, we encourage you to review our information with your doctor.
Chronic Myelomonocytic Leukemia (CMML)
Overall, the signs and symptoms of leukemia can affect men or women and do not differ by sex or gender.
The most common sign of chronic myelomonocytic leukemia (CMML) is having too many monocytes ( seen on a blood test).Having too many monocytes also causes many of the symptoms of CMML. These monocytes can settle in the spleen or liver, enlarging these organs. An enlarged spleen (called splenomegaly) can cause pain in the upper left part of the belly (abdomen). It can also cause people to notice they feel full too fast when they eat. If the liver gets too big (called hepatomegaly), it causes discomfort in the upper right part of the abdomen.
Low numbers of other types of blood cells cause many of the signs and symptoms of CMML:
Other symptoms can include weight loss, fever, and loss of appetite. Of course, many of these problems are caused more often by something other than cancer. If you're having symptoms, you should see a doctor so a cause can be found.
The American Cancer Society medical and editorial content team
Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as journalists, editors, and translators with extensive experience in medical writing.
Myelodysplastic/Myeloproliferative Neoplasms Treatment (PDQ) - Patient Version. August 12, 2015. Accessed on October 4, 2017 at www.cancer.gov/types/myeloproliferative/patient/mds-mpd-treatment-pdq#section/_278.
Last Revised: February 27, 2024
American Cancer Society medical information is copyrighted material. For reprint requests, please see our Content Usage Policy.
Sign up to stay up-to-date with news, valuable information, and ways to get involved with the American Cancer Society.