Key Statistics for Chronic Lymphocytic Leukemia
The American Cancer Society's estimates for chronic lymphocytic leukemia (CLL) in the United States for 2025 are:
- About 23,690 new cases of CLL (14,340 in males and 9,350 in females)
- About 4,460 deaths from CLL ( 2,810 in males and 1,650 in females)
CLL accounts for about 1 in 3 new cases of leukemia in the US, and about 1% of cancers overall.
CLL is slightly more common among men than women, but the average lifetime risk of getting CLL for both sexes is about ½ of 1%.
CLL mainly affects older adults. The average age of people when they are diagnosed is around 70 years. It's rarely seen in people under age 40, and it's extremely rare in children.
Visit the American Cancer Society’s Cancer Statistics Center for more key statistics.
- Written by
- References
The American Cancer Society medical and editorial content team
Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as editors and translators with extensive experience in medical writing.
American Cancer Society. Cancer Facts & Figures 2025. Atlanta: American Cancer Society; 2025.
National Cancer Institute. Cancer Stat Facts: Leukemia-Chronic Lymphocytic Leukemia (CLL). 2024. Accessed at https://seer.cancer.gov/statfacts/html/clyl.html on June 6, 2024.
Last Revised: January 16, 2025
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