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Surgery for Acute Myeloid Leukemia (AML)

Surgery has a very limited role in the treatment of acute myeloid leukemia (AML). Because leukemia cells are spread widely throughout the bone marrow and blood, it’s not possible to cure this type of cancer with surgery. Surgery rarely  is used even in the diagnosis of AML, since this can usually be done with a bone marrow aspirate and biopsy.

Surgery to place a central venous catheter

Often before chemotherapy for AML starts, a minor type of surgery is done to place a small flexible tube, called a central venous catheter (CVC) (also known as a central line or venous access device), into a large vein in the chest. This may be done by a surgeon in the operating room, or by a special type of radiologist. The end of the tube stays just under the skin or sticks out in the chest area or upper arm.

The CVC can be left in place during treatment (often for several months) to give intravenous (IV) medicines, such as chemotherapy, and to take blood samples for tests. This lowers the number of needle sticks needed during treatment.

If you have a CVC, it is very important to learn how to care for it to keep it from getting infected. Your cancer care team will teach you or a caregiver how to take care of your CVC.

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Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

 

Larson RA. Acute myeloid leukemia: Induction therapy in medically fit adults. UpToDate. 2024. Accessed at
https://www.uptodate.com/contents/acute-myeloid-leukemia-induction-therapy-in-medically-fit-adults on December 3, 2024.

National Cancer Institute. Acute Myeloid Leukemia Treatment (PDQ)–Health Professional Version. 2024. Accessed at https://www.cancer.gov/types/leukemia/hp/adult-aml-treatment-pdq on December 3, 2024.

National Comprehensive Cancer Network. NCCN Practice Guidelines in Oncology (NCCN Guidelines): Acute Myeloid Leukemia. V.3.2024. Accessed at https://www.nccn.org on December 3, 2024.

 

 

Last Revised: March 4, 2025

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